Peer-Reviewed Journal Details
Mandatory Fields
Mondal M.;Panda M.;Davis N.;McKee V.;Kerrigan N.
2019
January
Chemical Communications
Asymmetric synthesis of cyclopentanones through dual Lewis acid-catalysed [3+2]-cycloaddition of donor-Acceptor cyclopropanes with ketenes
Published
5 ()
Optional Fields
55
90
13558
13561
© The Royal Society of Chemistry 2019. When InBr3-EtAlCl2 (15-30 mol%) was used as a dual Lewis acid system to promote the formal [3+2]-cycloaddition of enantioenriched donor-Acceptor cyclopropanes with ketenes, cyclopentanones were formed in good to excellent yields (84-99%, 18 examples), and with excellent transfer of chirality (15 examples, 90% ee to >99% ee).
1359-7345
10.1039/c9cc07477e
Grant Details