Peer-Reviewed Journal Details
Mandatory Fields
Koutnik A.;D'Agostino D.;Egan B.
2019
January
Trends in Endocrinology and Metabolism
Anticatabolic Effects of Ketone Bodies in Skeletal Muscle
Published
()
Optional Fields
acetoacetate atrophy cachexia inflammation muscle protein breakdown β-hydroxybutyrate
© 2019 Elsevier Ltd The ketone bodies acetoacetate (AcAc) and β-hydroxybutyrate (βHB) are the subject of renewed interest given recently established pleiotropic effects regulating inflammation, oxidative stress, and gene expression. Anticatabolic effects of β-hydroxybutyrate have recently been demonstrated in human skeletal muscle under inflammatory insult, thereby expanding upon the wide-ranging therapeutic applications of nutritional ketosis.
1043-2760
10.1016/j.tem.2019.01.006
Grant Details