© The Authors. Combining Translation Memory (TM) with Statistical Machine Translation (SMT) together has been demonstrated to be beneficial. In this paper, we present a discriminative framework which can integrate TM into SMT by incorporating TM-related feature functions. Experiments on English-Chinese and English-French tasks show that our system using TM feature functions only from the best fuzzy match performs significantly better than the baseline phrasebased system on both tasks, and our discriminative model achieves comparable results to those of an effective generative model which uses similar features. Furthermore, with the capacity of handling a large amount of features in the discriminative framework, we propose a method to efficiently use multiple fuzzy matches which brings more feature functions and further significantly improves our system.