Ibrahim, AA;Smith, SM;Henson, S;Kerrigan, NJ

2009

December

Tetrahedron Letters

Synthesis of 1,3-diketones through ring-opening of ketoketene dimer beta-lactones

Published

11 ()

ALPHA-AMINO KETONES DIMETHYLKETENE DIMER ASYMMETRIC-SYNTHESIS ORGANOLITHIUM REAGENTS CHEMISTRY CLEAVAGE STEREOCHEMISTRY PROPIOLACTONE KETONIZATION DIMERIZATION

50

6919

6922

The reaction of ketoketene dimers with organolithium reagents afforded 1,3-diketones in good to excellent yields, and with good diastereoselectivity in some cases. (C) 2009 Elsevier Ltd. All rights reserved.

OXFORD

0040-4039

10.1016/j.tetlet.2009.09.158