Mandatory Fields

Authors

McStay, N.; Molphy, Z.; Gathergood, N.; Kellett. A.

Year

2017

Month

Unknown

Journal

Symmetry

Title

Opioid architectures as new DNA binding molecules

Status

Published

Times Cited

()

Optional Fields

Search Keyword

Volume

Issue

Start Page

195

End Page

198

Abstract

Herein we report the discovery of C3 symmetric opioid architectures as efficient DNA binding molecules. To our knowledge these agents are the first opioid based structures with nucleic acid recognition properties. These architectures may now pave the way toward the development of a new class of semi-synthetic DNA binding molecule with potential applications in gene delivery.

Publisher Location

ISBN / ISSN

2226-1877

Edition

URL

http://journal-scs.symmetry.hu/content-pages/volume-28-number-2-pages-161-240-2017/

DOI Link

http://journal-scs.symmetry.hu/content-pages/volume-28-number-2-pages-161-240-2017/

Grant Details

Funding Body

Grant Details

This work was supported by the Marie Skłodowska-Curie Innovative Training Network (ITN) ClickGene (H2020-MSCA-ITN-2014-642023), http://www.clickgene.eu/, FP7 ERA Chairs program No. 621364 (TUTIC-Green) and the Irish Research Council Government of Ireland Postgraduate Scheme (GOIPG/2013/826).