Peer-Reviewed Journal Details
Mandatory Fields
Morrin, A;Wilbeer, F;Ngamna, O;Moulton, SE;Killard, AJ;Wallace, GG;Smyth, MR
2005
March
Electrochemistry Communications
Novel biosensor fabrication methodology based on processable conducting polyaniline nanoparticles
Published
74 ()
Optional Fields
ELECTRODE GLUCOSE DISPERSIONS COMPOSITE LACTATE OXIDASE FILMS
7
317
322
This work investigates polyaniline (PANI) nanoparticles, (synthesised using dodecylbenzenesulphonic acid (DBSA) as a dopant), as a novel, highly processable, non-diffusional mediating species in an enzyme biosensing application. These nanoparticles are readily dispersed in aqueous media which helps overcome some of the processability issues traditionally associated with polyaniline. Modification of screen-printed electrodes was readily achieved with these aqueous nanoparticle dispersions, where the nanoparticles were simply cast by a drop-coating method onto the surface. After suitable pH adjustment, it was shown that horseradish peroxidase (HRP) enzyme could be added to the dispersion, and cast simultaneously with the conducting polyaniline. This effective fabrication method involves no electrochemical steps, and as such is easily amenable to mass production. The feasibility of casting enzyme with polyaniline nanoparticles is demonstrated in this short communication. More accurate deposition of protein-containing inks onto screen-printed carbon working electrodes could in the future transfer the drop-coating protocol from manual deposition to large-scale production by mechanical methods such as ink-jet printing. (C) 2005 Elsevier B.V. All rights reserved.
NEW YORK
1388-2481
10.1016/j.elecom.2005.01.014
Grant Details