This paper presents a set of experiments on Domain Adaptation of Statistical Machine Translation systems. The experiments focus on Chinese-English and two domain-specific corpora. The paper presents a novel approach for combining multiple domain-trained translation models to achieve improved translation quality for both domain-specific as well as combined sets of sentences. We train a statistical classifier to classify sentences according to the appropriate domain and utilize the corresponding domain-specific MT models to translate them. Experimental results show that the method achieves a statistically sig nificant absolute improvement of 1.58 BLEU (2.86% relative improvement) score over a translation model trained on combined data, and considerable improvements over a model using multiple decoding paths of the Moses decoder, for the combined domain test set. Furthermore, even for domain-specific test sets, our approach works almost as well as dedicated domain-specific models and perfect classification.